Is CXCR4 a GPCR?

Is CXCR4 a GPCR? C-X-C chemokine receptor 4 (CXCR4) is a GPCR that undergoes receptor internalization and recycling upon stimulation with its cognate ligand, C-X-C chemokine 12 (CXCL12). What kind of receptor is CXCR4? alpha-chemokine receptor CXCR-4 is an alpha-chemokine receptor specific for stromal-derived-factor-1 (SDF-1 also called CXCL12), a molecule Read more…