What is the most effective treatment for postmenopausal osteoporosis?
Bisphosphonates are the drugs of choice for preventing and treating postmenopausal osteoporosis. Alternatives for patients who cannot take bisphosphonates include raloxifene and calcitonin salmon.
Which medication should be administered yearly to a postmenopausal patient with osteoporosis?
Bisphosphonates. AACE/ACE, ACR, NAMS, and the Endocrine Society recommend bisphosphonates, excluding ibandronate, as a first-line option for the prevention and/or treatment of osteoporosis in postmenopausal women, men, and/or GIO patients (Table 2).
What are the long term side effects of zoledronic acid?
Blurred vision or other change in vision.
How long do side effects last after zoledronic acid infusion?
The majority of the side effects, such as fever and chills, pain in the muscles or joints, and headache, occur within the first three days following the dose of Zoledronic acid 5 mg. The symptoms are usually mild to moderate and go away within three days.
What are the side effects of zoledronic acid infusion?
The following side effects are common (occurring in greater than 30%) for patients taking zoledronic acid:
- Ostealgia.
- Nausea.
- Fever usually mild and short lived.
- Fatigue.
- Anemia.
- Vomiting.
- Constipation.
- Flu-like symptoms; mild fever sometimes accompanied by malaise, chills, fatigue and flushing.
Is zoledronic acid used for osteoporosis?
Zoledronic acid injection is also used to treat Paget’s disease of the bone in men and women. It is also used in men with osteoporosis and in women with osteoporosis who have gone through menopause. This medicine is used to reduce the risk of having more fractures in patients who have had a recent hip fracture.
Does zoledronic acid weaken the immune system?
In addition to its effects on bone cells, ZOL has profound effects on the immune system, including a plethora of immune cell subsets expressing the mevalonate pathway enzymes, leading to a general increase in anti-tumour immunity [65].
What happens after zoledronic acid infusion?
You may experience a reaction during the first few days after you receive a dose of zoledronic acid injection. Symptoms of this reaction may include flu-like symptoms, fever, headache, chills, and bone, joint or muscle pain.