What is the genome of dengue virus?
The dengue virus genome is a single strand of RNA. It is referred to as positive-sense RNA because it can be directly translated into proteins. The viral genome encodes ten genes (Figure 2). The genome is translated as a single, long polypeptide and then cut into ten proteins.
What is the genome size of dengue virus?
about 11,000 bases
DENV is a single stranded and positive polarity RNA virus with a genome of about 11,000 bases in length [3], and belongs to the genus Flavivirus, family Flaviviridae [4].
What are the 4 serotypes of dengue?
Dengue is caused by a virus of the Flaviviridae family and there are four distinct, but closely related, serotypes of the virus that cause dengue (DENV-1, DENV-2, DENV-3 and DENV-4). Recovery from infection is believed to provide lifelong immunity against that serotype.
Is dengue virus RNA or DNA?
Dengue virus (DENV) is an enveloped and positive‐strand RNA virus that belongs to the genus Flavivirus of the Flaviviridae family [1].
Is dengue virus lytic or lysogenic?
The Dengue virus goes through the lysogenic cycle. B is correct. In both creatures, the viral DNA is replicating both its DNA and the capsid coverings it needs to survive in the environment. This is known as the lytic cycle.
What is serotype in virus?
Serotypes are groups within a single species of microorganisms, such as bacteria or viruses, which share distinctive surface structures.
How does dengue virus replicate?
It is composed of the viral genome and capsid proteins surrounded by an envelope and a shell of proteins. After infecting a host cell, the dengue virus hijacks the host cell’s machinery to replicate the viral RNA genome and viral proteins. Newly synthesized dengue viruses can go on to infect other host cells.
What type of genome does West Nile virus have?
The WNV genome is a single-stranded, positive sense RNA of ~11,000 nt [3]. The genome functions as the only viral mRNA and also as the template for synthesis of the complementary minus strand RNA.
Is dengue a genetic disease?
Interpretation. There is a strong genetic effect that predisposes to risk of DHF/DSS and DF. The genetic risk for DHF/DSS is higher than that for DF when compared to controls, and this effect persists across multiple ancestries.
When did dengue come to India?
In India, the first epidemic of clinical dengue-like illness was recorded in Madras (now Chennai) in 1780 and the first virologically proved epidemic of dengue fever (DF) occurred in Calcutta (now Kolkata) and Eastern Coast of India in 1963-1964.
Is dengue lytic or lysogenic?
lysogenic cycle
The Dengue virus goes through the lysogenic cycle. B is correct. In both creatures, the viral DNA is replicating both its DNA and the capsid coverings it needs to survive in the environment. This is known as the lytic cycle.
Is dengue a retrovirus?
The difference in abundance between the two areas does not affect the impact of dengue virus on humans (10). Since, DENV is a retrovirus, it follows the traditional retroviral infection pathway This means turning its RNA into host cell DNA and then making copies from the host machinery.