What is anaplastic multiple myeloma?
Anaplastic multiple myeloma (AMM) is a rare variant of multiple myeloma with an aggressive clinical course. Studies have suggested that this variant is a form of aggressive transformation or a clonal evolution of the initial plasma cell clone.
What are the types of plasma cells?
The current findings suggest that after the process of affinity maturation in germinal centers, plasma cells develop into one of two types of cells: short-lived plasma cells (SLPC) or long-lived plasma cells (LLPC).
What is anaplastic Plasmacytoma?
Anaplastic plasmacytoma: a rare tumor presenting as a pathological fracture in a younger adult. Skeletal Radiol.
Are plasma cells malignant?
Plasma cell neoplasms can be benign (not cancer) or malignant (cancer). There are several types of plasma cell neoplasms. Multiple myeloma and other plasma cell neoplasms may cause a condition called amyloidosis. Age can affect the risk of plasma cell neoplasms.
What are villi and plasma cells?
Plasma cells are derived from B-lymphocytes and produce large quantities of antibodies. They are abundant wherever antigens may enter the body, such as the gastrointestinal tract and the respiratory system. Many plasma cells are found in the connective tissue of the small intestine underneath the epithelium of villi .
Are there cells in plasma?
Donating Platelets Plasma is the liquid portion of blood; our red and white blood cells and platelets are suspended in plasma as they move throughout our bodies.
Which antibody is produced by plasma cells?
Immunoglobulins (Ig) are Y-shaped protein molecules, called antibodies, that are made by plasma cells. An immunoglobulin is made up of 4 parts called chains. There are 2 light chains and 2 heavy chains that are attached to each other by chemical bonds. There are 5 types of immunoglobulins – IgG, IgA, IgM, IgD and IgE.