What is a Scheie stripe?

Unlike other causes of pigment liberation, however, pigment deposition in PDS can occur at the insertion of lens zonular fibers into the posterior lens capsule and cause a pattern known as a Zentmayer ring or Scheie stripe.

How do you manage pigment dispersion syndrome?


  1. Observation and close follow-up of patients at risk.
  2. Medical therapy if glaucoma present (or at risk for glaucoma)
  3. Surgical therapy includes: Peripheral laser iridotomy to flatten the iris and eliminate posterior bowing of the iris (thereby minimizing pigment liberation)

What causes Krukenberg spindle?

Krukenberg’s spindle is the name given to the pattern formed on the inner surface of the cornea by pigmented iris cells that are shed during the mechanical rubbing of posterior pigment layer of the iris with the zonules that are deposited as a result of the currents of the aqueous humor.

What is pigment dispersion glaucoma?

Pigmentary glaucoma and PDS occur when pigment is released from the iris pigment epithelium due to rubbing of the posterior iris against the anterior lens zonules. The disease is more prevalent in males, and typically presents in the 3rd-4th decade of life.

What is iris Transillumination?

Bilateral acute iris transillumination (BAIT) is a recently defined disease characterized with bilateral acute, severe pigment dispersion of iris and pupil sphincter paralysis.

What is iris transillumination defects?

The disease has characteristics of bilateral enlargement of the corneal diameter and a deep anterior eye chamber, without an elevation in intraocular pressure. It can manifest with mild to moderate myopia as well as photophobia and iridodonesis (due to iris hypoplasia).

Will I go blind from pigmentary glaucoma?

Blindness due to pigmentary glaucoma is rare. In a study of 113 patients with PDS and pigmentary glaucoma, three eyes in two patients were blind. Progression of the disease, however, is common.

Can pigment dispersion disappear?

The onset of pigment dispersion syndrome, which is an autosomal dominant disorder, typically occurs when patients are in their early 20s, but the condition begins to regress with increasing age, enlargement of the lens, and the loss of accommodation due to the onset of presbyopia.

What does a Pachymeter do?

A pachymeter is a medical device used to measure the thickness of the eye’s cornea. It is used to perform corneal pachymetry prior to refractive surgery, for Keratoconus screening, Cataract, LRI surgery and is useful in screening for patients suspected of developing glaucoma among other uses.

Why are my eyes leaking?

Pigment-dispersion syndrome is an eye disorder that occurs when pigment granules that normally adhere to the back of the iris (the colored part of the eye) flake off into the clear fluid produced by the eye (aqueous humor).

What are transillumination defects?

Definition. Transmission of light through the iris as visualized upon slit lamp examination or infrared iris transillumination videography. The light passes through defects in the pigmentation of the iris. [ from HPO]

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